The pre-condensation state of the dimodular NRPS protein LgrA
收藏Protein Data Bank Japan2025-02-19 更新2026-04-19 收录
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The pre-condensation state of the dimodular NRPS protein LgrA Descriptor: (2~{R})-~{N}-[3-[2-[[(2~{S})-2-formamido-3-methyl-butanoyl]amino]ethylamino]-3-oxidanylidene-propyl]-3,3-dimethyl-2-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-butanamide, GLYCEROL, Linear gramicidin synthase subunit A, ... Authors: Pistofidis, A, Schmeing, T.M. Deposit date: 2024-04-13 Release date: 2024-11-20 Last modified: 2025-02-19 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures and mechanism of condensation in non-ribosomal peptide synthesis. Nature, 638, 2025
双模块非核糖体肽合成酶(non-ribosomal peptide synthetase, NRPS)蛋白LgrA的缩合前状态相关描述:(2R)-N-[3-[2-[[(2S)-2-甲酰胺基-3-甲基丁酰基]氨基]乙基氨基]-3-氧代丙基]-3,3-二甲基-2-羟基-4-[羟基-二氧代-λ⁶-膦基]氧基丁酰胺、甘油(Glycerol)、线性短杆菌肽合酶亚基A等。作者:Pistofidis, A、Schmeing, T.M. 提交日期:2024-04-13 发布日期:2024-11-20 最后修改日期:2025-02-19 实验方法:X射线衍射(2.9 Å) 引用文献:《非核糖体肽合成过程中的缩合结构与机制》,《自然》(*Nature*),第638卷,2025年
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2024-04-13



