Gut microbiota may predict metachronous adenoma in CRC patients after operation-validation cohort

The occurrence of metachronous colorectal cancer (CRC) in patients after surgery has been well documented. Despite high risk, there is a lack of reliable factors or models to be used for predicting the development of metachronous CRC. The objectives of this study were to examine mucosal and fecal microbiota, and to assess their values in the prediction of metachronous colorectal adenoma among CRC patients who underwent surgical removal of their primary CRC.