STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound MSA-2

STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound MSA-2 Descriptor: 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain Authors: Lesburg, C.A. Deposit date: 2019-10-05 Release date: 2020-08-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.74 Å) Cite: An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020STING C端结构域与非环状二核苷酸化合物MSA-2的复合物 描述项：4-(5,6-二甲氧基-1-苯并噻吩-2-基)-4-氧代丁酸，以及泛素样蛋白SMT3与干扰素刺激蛋白C端结构域的融合蛋白 作者：莱斯伯格（Lesburg, C.A.） 提交日期：2019-10-05 发布日期：2020-08-19 最后修改日期：2023-10-11 实验方法：X射线衍射（分辨率1.74埃） 引用：《一种具有抗肿瘤活性的口服非核苷酸STING激动剂》，《科学》，369卷，2020年