Risk of colon cancer according to baseline quintiles of one-carbon nutrient intake by BRAF mutation status in tumors among 88,691 women in the Nurses' Health Study (1980–2002).

‡Age adjusted only.*All models are adjusted for age (continuous), energy intake, gender, screening sigmoidoscopy, family history of colorectal cancer, aspirin use, smoking, physical activity in METs, baseline body mass index, a history of colon polyps, beef intake, calcium, multi-vitamin use, and baseline folate, vitamin B6, B12, methionine, and alcohol if not primary exposure.