Effect of whole-body deletion of Gclc on the liver
收藏NIAID Data Ecosystem2026-05-02 收录
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资源简介：
The rate-limiting step in glutathione (GSH) synthesis is controlled by glutamate-cysteine ligase catalytic subunit. To investigate the impact of GSH in vivo, we induced a deletion of Gclc using a Gclcf/f Rosa26-CreERT2 mouse model and harvested liver tissue for analysis. Liver tissue was harvested from WT and KO mice approximately two weeks after treatment with tamoxifen to induce Cre activity and Gclc deletion.
创建时间：
2024-08-16
