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Structure of NEK2 bound to CCT

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Structure of NEK2 bound to CCT Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-{6-[(1-METHYLPIPERIDIN-4-YL)OXY]-1H-BENZIMIDAZOL-1-YL}-3-{(1R)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHOXY}THIOPHENE-2-CARBOXAMIDE, ... Authors: Mas-Droux, C, Bayliss, R. Deposit date: 2010-08-05 Release date: 2011-03-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Benzimidazole Inhibitors Induce a Dfg-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J.Med.Chem., 54, 2011
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2010-08-05
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