Photo-tunable Protein Nitration by Sensitizer Tris(bipyridine)-Ruthenium(II) Chloride complex_Glu-C digestion Dataset
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Post-translational modifications of proteins are a diverse source of variability that impacts on their functions, localization, regulation, and lifetime; and oxidative modifications are usually associated to pathological and degenerative conditions. Photosensitizers have been employed to promote oxidative modifications and model molecular aspects of diseases. Therefore, we provide the MS/MS raw data from the application of the novel light-controlled Ru(bpy)3+2/APS/NaNO2 system to nitrate four different model proteins. Each protein dataset contains raw data from treated and untreated samples.
蛋白质的翻译后修饰是一类多样的变异来源,可影响其功能、定位、调控过程与存活时长;而氧化修饰通常与病理及退行性疾病状态相关。光敏剂已被用于诱导氧化修饰,并模拟疾病的分子层面特征。为此,本数据集提供了利用新型光控Ru(bpy)3+2/过硫酸铵(Ammonium Persulfate, APS)/亚硝酸钠(Sodium Nitrite, NaNO2)体系,对四种不同模式蛋白质进行硝基化修饰的串联质谱(MS/MS)原始数据。每份蛋白质数据集均包含处理组与未处理组的原始数据。



