Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304
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Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304 Descriptor: (7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... Authors: Hsu, H.-C, Li, H. Deposit date: 2023-09-28 Release date: 2023-12-20 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (2.04 Å) Cite: Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors. Nat Commun, 14, 2023
与抑制剂TDI-8304结合的人类组成型20S蛋白酶体复合物结构
描述项：(7S,10S,13S)-N-环戊基-10-[2-(吗啉-4-基)乙基]-9,12-二氧代-13-(2-氧代吡咯烷-1-基)-2-氧杂-8,11-二氮杂双环[13.3.1]十九碳-1(19),15,17-三烯-7-甲酰胺、蛋白酶体α亚基1型、蛋白酶体α亚基2型……
作者：Hsu, H.-C、Li, H.
入库日期：2023-09-28
发布日期：2023-12-20
最后修改日期：2024-01-03
检测方法：电子显微镜（分辨率2.04 Å）
引用文献：《揭示恶性疟原虫对蛋白酶体抑制剂的耐药机制与交叉敏感性》，《自然·通讯》，14卷，2023年
创建时间：
2023-09-28
