ASF1 acts with RIF1 to promote DNA end-joining in BRCA1 deficient cells
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
RIF1 acts downstream of 53BP1 to coordinate DNA double strand break repair pathway choice between non-homologous end joining (NHEJ) and homologous recombination (HR). Here we identified ASF1 as an endogenous RIF1-associated protein. We showed that ASF1 forms complex with RIF1 and regulates RIF1-dependent functions in DNA damage response.
创建时间：
2022-06-09
