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Transcriptome profiling of muscle stem cells from control, mdx and Sirt6 knockout on mdx background mice. Transcriptome profiling of muscle stem cells from control, mdx and Sirt6 knockout on mdx background mice

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NIAID Data Ecosystem2026-03-12 收录
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In this study, Pax7-Cre mediated inactivation of Sirt6 in mdx mice resulted in profound improvement of the mdx phenotype at the functional level. To study the underlying molecular mechanisms we performed RNA-seq of MuSCs from control, mdx and Sirt6mKO/mdx mice. Overall design: RNA-seq analysis of MuSCs from control (wild type), mdx and Sirt6mKO/mdx mice

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2021-03-16
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