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Rag1KO RORgtcre Setd2 flox NKp46- ILC3 RNAseq
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创建时间：
2022-02-24
相关数据集
RNA-sequencing of renal cells from Setd2-wildtype PKD and Setd2-knlckout ccRCC mice.. RNA-sequencing of renal cells from Setd2-wildtype PKD and Setd2-knlckout ccRCC mice.
To explore potential role of SETD2 in PKD-ccRCC transition in vivo, we generated a PKD mouse model by overexpressing oncogene c-MYC under the control of the Ksp promoter (KM mice), and knockout Setd2
NIAID Data Ecosystem40
DataSheet1_Elevated levels of the methyltransferase SETD2 causes transcription and alternative splicing changes resulting in oncogenic phenotypes.ZIP
The methyltransferase SETD2 regulates cryptic transcription, alternative splicing, and the DNA damage response. It is mutated in a variety of cancers and is believed to be a tumor suppressor. Counteri
NIAID Data Ecosystem20
Setd2 knockdown.. Setd2 knockdown.
Setd2 knockdown leads to subtle but significant changes in gene expression and alternative splicing. Overall design: Three independent transfections of NIH/3T3 cells were performed for two Setd2-speci
NIAID Data Ecosystem20
Exosome from A498 cellular supernatant
Set domain-containing 2 (SETD2) is the most frequently mutated gene among all the histone methyltransferases (HMTs) in Clear cell renal cell carcinoma (ccRCC). Loss of function of SETD2 is significant
NIAID Data Ecosystem30
RNA-sequencing of wild-type versus SETD2-null 786-O and HKC cells.
RNA-seq analysis was performed from wild-type and SETD2-null cells in order to gauge changes in gene expression following loss of SETD2 methylation activity. We identified 4 genes that were commonly u
NIAID Data Ecosystem20
