Transporter associated with antigen processing (TAP) EQ mutant bound to the viral protein bUL49.5 in the outward-facing kinked state
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Transporter associated with antigen processing (TAP) EQ mutant bound to the viral protein bUL49.5 in the outward-facing kinked state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Antigen peptide transporter 1, Antigen peptide transporter 2, ... Authors: Lee, J, Manon, V, Chen, J. Deposit date: 2025-04-17 Release date: 2025-09-10 Last modified: 2026-03-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structurally diverse viral inhibitors converge on a shared mechanism to stall the antigen transporter TAP. Proc.Natl.Acad.Sci.USA, 122, 2025
本数据集为结合病毒蛋白bUL49.5的抗原加工相关转运蛋白(Transporter associated with antigen processing, TAP)EQ突变体,其呈现向外开口的扭构状态。 描述项:腺苷-5'-三磷酸、抗原肽转运蛋白1、抗原肽转运蛋白2…… 作者:Lee J、Manon V、Chen J 存档日期:2025-04-17 发布日期:2025-09-10 最后修改日期:2026-03-18 实验方法:电子显微镜(3.1 Å) 引用文献:《结构多样的病毒抑制剂通过共同机制阻断抗原转运蛋白TAP》,《美国国家科学院院刊》,122卷,2025年



