Apolipoprotein E4 (APOE4) is the strongest known genetic risk factor for late-onset Alzheimer’s disease (AD). Conditions of stress or injury induce APOE expression within neurons, but the exact roles
Additional file 1: Supplementary Table 1. List of post-translational modifications detected on tau across AD, AGD, CBD, PiD and PSP. Supplementary Table 2. Summary of human tau interactome and localis
Multiple sclerosis (MS) and its preclinical models are characterized by marked changes in neuroplasticity, including excitatory/inhibitory imbalance and synaptic dysfunction that are believed to under
