Rhodium-Catalyzed, Remote Terminal Hydroarylation of Activated Olefins through a Long-Range Deconjugative Isomerization

The Rh-catalyzed, remote terminal
hydroarylation of active olefins
at the C7-position of indoles and the ortho-position
of indolines and anilines with the appropriate choice of a N-PtBu2 directing
group through long-range deconjugative isomerization has been reported.
This transformation not only overcomes the conjugate rule of Michael
acceptors but also controls the positional selectivity of indoles,
representing a significant advancement in both alkene isomerization
and the C–H alkylation of indoles.