Protein acetylation as a diet-modifiable biomarker of colorectal cancer risk

Study hypothesis: We hypothesise that the reduced risk of colorectal cancer through increased fibre intake is mediated in part through changes in global protein acetylation. Primary outcome(s): Altered faecal short chain fatty acid (SCFA) production. In the cross-sectional arm there is a single sampling timepoint and all primary and secondary measures are made at this point. For the intervention arm sampling is performed at baseline and after 8 weeks of intervention.