Secreted Clusterin Inhibits Tumorigenesis by Modulating Tumor Cell and Macrophage in Human Meningioma. Secreted Clusterin Inhibits Tumorigenesis by Modulating Tumor Cell and Macrophage in Human Meningioma
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA851709
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资源简介：
Our single-cell transcriptomic dataset exceeds the scale of previous efforts to systematically characterize meningioma. We identified CLU is tumor suppresser, also promote the anti-tumor capability of macrophage, that why CLU decreased in meningioma malignancy. HDACi may inhibit meningioma by increasing CLU expression. Therefore, promoting CLU expression maybe a great strategy for meningioma therapeutics. Overall design: Single-cell analysis of 18 specimens from 13 patients: 2 with meningeal, 8 with grade I, 4 with grade II and 4 with grade III. **Raw data are not provided due to patient privacy concerns**
创建时间：
2022-06-22
