Estimated proportion of heritability explained by SNPs for various diseases.

indicates the number of SNP markers used in the model being evaluated. All other values indicate the estimated proportion of variance in additive genetic liability accounted for by known SNP associations. The columns labeled with rely on the risk allele frequencies in the control populations, as provided in the NHGRI association list, whereas the columns labeled with rely on population allele frequencies in the 1000 Genomes dataset. The columns labeled with use the raw odds ratios provided in the NHGRI association list, whereas the columns labeled with use odds ratios that have been adjusted for winner's curse bias. The final column provides references for other estimates of from the literature.