BIOGRID CURATED DATA FOR LPX1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for LPX1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Peroxisomal matrix-localized lipase; required for normal peroxisome morphology; contains a peroxisomal targeting signal type 1 (PTS1) and a lipase motif; peroxisomal import requires the PTS1 receptor, Pex5p and self-interaction; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; oleic acid inducible

蛋白质-蛋白质、遗传和化学相互作用数据集，针对LPX1（酿酒酵母S288c），由BioGRID（https://thebiogrid.org）编纂；定义：过氧化物酶体基质定位的脂肪酶；对于正常过氧化物酶体形态至关重要；含有过氧化物酶体靶向信号类型1（PTS1）和脂肪酶基序；过氧化物酶体导入需要PTS1受体Pex5p及自相互作用；由Yrm1p与参与多药耐药性相关基因协同转录激活；油酸诱导型。