2-photon calcium imaging in S1 of enriched and normally housed mice during individual deflection of 9 whiskers

This data consists of 2-photon calcium imaging data from excitatory neurons in L2/3 and L4 of barrel (vibrissal somatosensory) cortex of anesthetized mice during deflection of 9 whiskers on the face individually in random order. Experiments were performed in Drd3-Cre mice (L2/3 pyramidal neurons) and Scnn1a-Tg-Cre mice (L4 excitatory neurons) expressing GCaMP6s via viral targeting. For each strain there are two experimental groups: mice in one group (EN) were housed with environmental enrichment and one group (NH) without. Data come from ~30-150 individual neurons per mouse (5-7 mice per experimental group) and consist of raw fluorescence and deltaF/F time series for each neuron, stimulus files aligning stimulus identity and timing to time series, and anatomical positions for each cell relative to each of 9 barrel columns corresponding to stimulated whiskers. All data are stored in .mat files. Results from the experiments are described in: LeMessurier et al. eLife 2019;8:e46321. DOI: https://doi.org/10.7554/eLife.46321 Amy M. LeMessurier, Daniel E. Feldman. bioRxiv 447508; doi: https://doi.org/10.1101/447508 MATLAB code used for processing data is available at: https://github.com/alemessurier/imaging_analysis_pipeline Sample movies from one mouse are available at: https://drive.google.com/drive/folders/1tpNpZWGiPoMCf5lb7dXAPFKZno6VQ0xV?usp=sharing