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Long-range repression in the Drosophila embryo.

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PubMed Central1996-09-03 更新2026-05-02 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC38424/
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资源简介:
Transcriptional repressors can be characterized by their range of action on promoters and enhancers. Short-range repressors interact over distances of 50-150 bp to inhibit, or quench, either upstream activators or the basal transcription complex. In contrast, long-range repressors act over several kilobases to silence basal promoters. We describe recent progress in characterizing the functional properties of one such long-range element in the Drosophila embryo and discuss the contrasting types of gene regulation that are made possible by short- and long-range repressors. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1996-09-03
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