Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.

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Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1,3,4-oxadiazole,-benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Descriptor: 2-(BETA-D-GLUCOPYRANOSYL)-5-METHYL-1-BENZIMIDAZOLE, Glycogen phosphorylase, muscle form, ... Authors: Chrysina, E.D, Kosmopoulou, M.N, Tiraidis, C, Kardakaris, R, Bischler, N, Leonidas, D.D, Hadady, Z, Somsak, L, Docsa, T, Gergely, P, Oikonomakos, N.G. Deposit date: 2004-09-30 Release date: 2005-03-15 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site Protein Sci., 14, 2005

针对肌肉糖原磷酸化酶b（muscle glycogen phosphorylase b）抑制剂2-(β-D-吡喃葡萄糖基)-5-甲基-1,3,4-噁二唑、-苯并噻唑及-苯并咪唑开展的动力学与晶体学研究：全新结合位点的证据。描述符：2-(β-D-吡喃葡萄糖基)-5-甲基-1-苯并咪唑、糖原磷酸化酶（Glycogen phosphorylase）肌肉型…… 作者：Chrysina, E.D、Kosmopoulou, M.N、Tiraidis, C、Kardakaris, R、Bischler, N、Leonidas, D.D、Hadady, Z、Somsak, L、Docsa, T、Gergely, P、Oikonomakos, N.G 提交日期：2004年9月30日发布日期：2005年3月15日最后修改日期：2025年3月26日实验方法：X射线衍射（分辨率1.93 Å）引用文献：《针对肌肉糖原磷酸化酶b抑制剂2-(β-D-吡喃葡萄糖基)-5-甲基-1,3,4-噁二唑、苯并噻唑及苯并咪唑的动力学与晶体学研究：全新结合位点的证据》，发表于Protein Sci.，第14卷，2005年

创建时间：

2004-09-30