Hodgkin lymphoma in children, adolescents and young adults – a comparative study of clinical presentation and treatment outcome

Background: Hodgkin lymphoma (HL) treatment protocols for children, adolescents and young adults traditionally differ, but the biological and clinical justification for this remains uncertain. Material and methods: We compared age-dependent clinical presentation and treatment and outcome for 1072 classical HL patients 0–24 years diagnosed in Denmark (1990–2010) and Sweden (1992–2009) in pediatric (n = 315, Denmark

背景：针对儿童、青少年及年轻成人的霍奇金淋巴瘤（HL）治疗方案传统上存在差异，然而，其生物学和临床依据尚不明确。材料与方法：本研究对比了1990年至2010年在丹麦（n=315）及1992年至2009年在瑞典（n=315）确诊的1072例经典HL患者的年龄依赖性临床特征、治疗方案及预后。