uPA-31F

uPA-31F Descriptor: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B Authors: Buckley, B.J, Jiang, L.G, Huang, M.D, Kelso, M.J, Ranson, M. Deposit date: 2018-02-07 Release date: 2018-12-19 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer. J. Med. Chem., 61, 2018uPA-31F 结构描述符：3-氨基-5-(1-氮杂环庚基)-N-脒基-6-(2,4-二甲氧基嘧啶-5-基)吡嗪-2-甲酰胺（3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide），尿激酶型纤溶酶原激活物B链（Urokinase-type plasminogen activator chain B）；作者：Buckley, B.J.、Jiang, L.G.、Huang, M.D.、Kelso, M.J.、Ranson, M.；入库日期：2018-02-07；发布日期：2018-12-19；最后修改日期：2024-11-20；测试方法：X射线衍射（X-RAY DIFFRACTION），解析分辨率为1.65埃（Å）；引用文献：《6-取代六亚甲基阿米洛利（HMA）衍生物作为强效选择性人尿激酶型纤溶酶原激活物抑制剂的癌症治疗应用》，《J. Med. Chem.》，2018年，第61卷