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Characterization of SARS-CoV-2–Specific B Cell Responses in Breakthrough and Multiple Infection Cohorts

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE304643
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We analyzed the B cell responses after infection in two cohorts: individuals with breakthrough infections following SARS-CoV-2 vaccination and individuals with multiple SARS-CoV-2 infections. SARS-CoV-2–specific B cells were sorted from PBMCs obtained from both the breakthrough infection cohort and the multiple-infection cohort, and LIBRA-seq was used to assess their antigen reactivity to SARS-CoV-2 and gene expression profiles.
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2025-09-20
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