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Numbers of cases and controls (in 1000s of each, rounded up) required to attain a specified AUC using a panel of 100,000 markers that explains half the heritability of liability.

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Figshare2015-12-02 更新2026-04-29 收录
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π0, proportion of SNPs having no effect on disease. Max, maximum AUC achievable given the genetic variance of the marker panel. In parentheses, P-value threshold that maximises the AUC.

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2015-12-02
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