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Comparison of transcriptional profiles of (1) intestinal ILC3s isolated from WT and IL-17D-deficient mice; (2) CD93+ILC3s and CD93-ILC3s from WT mice

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https://www.ncbi.nlm.nih.gov/sra/SRP303828
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资源简介:
IL-17D/CD93 axis was essential for ILC3s hemostasis. In order to further understand how IL-17D-CD93 axis regulate ILC3s function, we conducted RNA-seq analysis of ILC3s. Overall design: Cell suspension were isolated from intestine of WT or IL-17D-deficient mice under steady state and ILC3s (live CD45lowCD3negCD19negCD90.2high) were sort purified. CD93+ or CD93- ILC3s were sorted from WT mice. RNA was isolated and RNA-seq was performed using BGISEQ-500 platform by BGI Genomics and successfully mapped to mouse genome.
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2021-05-23
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