Cell of origin epigenetic priming determines susceptibility to Tet2 oncogenic mutation

NIAID Data Ecosystem2026-05-02 收录

癌症表观遗传学

TET2基因突变

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE247970 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-06-06

Control ChIP-seq from HCT116 (ENCSR936ENS)

染色质免疫沉淀测序

癌症表观遗传学

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

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Supplementary Table S4 from Discovery of Candidate DNA Methylation Cancer Driver Genes

癌症表观遗传学

甲基化驱动基因

Copy number changes in MethSig CLL DNAme drivers.

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Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch [methylation]

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Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests t

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Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

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Prevention of chromatin destabilization by FACT is crucial for malignant transformation. Prevention of chromatin destabilization by FACT is crucial for malignant transformation

癌症表观遗传学

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Histone chaperone FACT is commonly expressed and essential for the viability of transformed but not normal cells and its expression levels correlate with poor prognosis in cancer patients. FACT binds

NIAID Data Ecosystem40

Cell of origin epigenetic priming determines susceptibility to Tet2 oncogenic mutation

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