Threshold surface density of gp120-CCR5 complexes for different Env clones.
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Estimates of the threshold surface density of gp120-CCR5 complexes, GCT, and the cooperativity factor, α, for 16 different transmitted or early founder viruses determined from fits of model predictions with experimental data [28] of cell-cell fusion in the presence of maraviroc (Fig. 6). 95% confidence intervals for the best-fit parameter estimates are shown in brackets. The corresponding IC50 values of maraviroc are also listed.
创建时间:
2011-05-27



