RNA-seq in neutrophils from patients with intracranial aneurysms

In this study, we explored transcriptional differences in human neutrophils from patients with intracranial aneurysms and a demographic and comorbidity paired population of controls Overall design: We compared differentially expressed genes among neutrophils from 11 blood samples from patients with intracranial aneurysms and 11 blood samples from paired controls. We used an independent, unpaired, corroboration cohort of 5 intracranial aneurysm patients and 5 control patients to confirm our findings.