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Multi-omics of Bohring-Opitz syndrome truncating ASXL1 mutations identify canonical and non-canonical Wnt signaling dysregulation [ATAC-seq Fibro]

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NIAID Data Ecosystem2026-05-02 收录
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We performed genome-wide chromatin accessibility analysis using data obtained from ATAC-seq of BOS patient and control individual fibroblast samples to dissect the chromatin regulating effects of truncating ASXL1 mutations. We performed genome-wide chromatin accessibility analysis using data obtained from ATAC-seq of BOS patient and control individual fibroblast samples. Comparative genome-wide chromatin accessibility analysis of ATAC-seq data for Bohring-Opitz syndrome patient fibroblast samples and control fibroblast samples.

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2025-01-28
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