Fig 6 – figure supplement 1: Stability of fEPSP slope during prolonged periods of sleep or wake

Time series data of thalamocortical evoked fEPSP slopes over the course of either sleep or wake dense epochs. (A) Hypnograms showing an example of a wake and sleep dense epoch. Black rectangles indicate example times in which stimulations were analyzed for this example. (B) FEPSP slopes during sleep dense epochs, measured in NREM (as illustrated by box around hypnogram on left). Epochs passing the >65% threshold are shown on left, and those passing the >75% threshold are shown on right. FEPSP slope was normalized to the beginning of each epoch. Each dot is data from one epoch, averaged over 10 minute bins; n = 4 animals. Blue line = mean, shading = SEM, black dotted line = 1 (i.e. no change). (C) Same as (B) but for REM events. (D) Same as (B) but normalized fEPSP slope during wake, measured during active wake. (E) Same as (D) but for quiet wake events.