Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling

RNAseq analysis revealled that the expression of Hedgehog and Wnt pathway members were altered by Pak2 gene knockout during mesotheliomagenesis. Overall design: RNA SEQUENCING ON PERITONEAL PRIMARY TUMORS was performed to compare the transcriptome changes during the formation of mesothelioma in different genotypes of mice