Crystal structure of human R180T variant of ORNITHINE AMINOTRANSFERASE at 1.8 Angstrom

Crystal structure of human R180T variant of ORNITHINE AMINOTRANSFERASE at 1.8 Angstrom Descriptor: Ornithine aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE Authors: Giardina, G, Montioli, R, Cellini, B, Cutruzzola, F, Borri Voltattorni, C. Deposit date: 2018-10-16 Release date: 2019-06-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: R180T variant of delta-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features. Febs J., 286, 2019

分辨率为1.8埃的人源鸟氨酸氨基转移酶（ORNITHINE AMINOTRANSFERASE）R180T突变体的晶体结构。描述项：线粒体鸟氨酸氨基转移酶，结合吡哆醛-5'-磷酸（PYRIDOXAL-5'-PHOSPHATE）。作者：Giardina G、Montioli R、Cellini B、Cutruzzola F、Borri Voltattorni C。沉积日期：2018-10-16。发布日期：2019-06-05。最后修改日期：2024-01-24。实验方法：X射线衍射（X-RAY DIFFRACTION，1.8 Å）。引用文献：与回旋形视网膜萎缩（gyrate atrophy）相关的δ-鸟氨酸氨基转移酶R180T突变体：生化、计算、X射线衍射与核磁共振研究揭示其催化特性，载于《FEBS杂志》（Febs J.），第286卷，2019年。