Clinical manifestations of hyperleukocytosis/leukostasis in all patients, patients with therapeutic leukapheresis plus chemotherapy and patients with chemotherapy only.

Patients receiving leukapheresis and chemotherapy showed significantly more clinical symptoms of leucostasis and a deregulated coagulation compared to the patients receiving chemotherapy only. This reflects the policy of leukapheresis in our hospital, since only patients with signs of leukocytosis underwent leukapheresis. Abbreviations: CPAP, continuous positive airway pressure; HD, hemodialysis; HF, hemofiltration; ITN, intubaton; LA, leukapheresis; PTT, partial thromboplastin time.