Polymorphism identification through exome and transcriptome analysis of pigs affected with umbilical hernia

Umbilical hernia (UH) is one of the most frequent defects affecting pig production, however, it also affects humans and other mammals. UH is characterized as an abnormal protrusion of the abdominal contents to the umbilical region, causing pain, discomfort and reduced performance in pigs. To clarify the genetic basis of swine umbilical hernia, this study aimed to identify polymorphisms and genes associated with UH in pigs through the whole-exome sequencing and additional transcriptome data analyses