Gene expression changes in beta-blocker treated neonatal hearts

The regeneration potential of the mammalian heart is limited. We found that treatment of beta-blocker robustly enhanced cardiomyocyte proliferation and promoted cardiac regeneration post myocardial infarction. To investigate the gene expression changes, we performed RNA-seq using the hearts treated with beta-blocker for 7 days. Overall design: mRNA profiles of neonatal control and beta-blocker treated hearts at P7