Inhibition of Isoniazid-Induced Expression of Mycobacterium tuberculosis Antigen 85 in Sputum: Potential Surrogate Marker in Tuberculosis Chemotherapy Trials

Name: Inhibition of Isoniazid-Induced Expression of Mycobacterium tuberculosis Antigen 85 in Sputum: Potential Surrogate Marker in Tuberculosis Chemotherapy Trials
Creator: American Society for Microbiology (ASM)
License: 暂无描述

PubMed Central2026-05-16 收录

下载链接：

https://pmc.ncbi.nlm.nih.gov/articles/PMC90462/

下载链接

链接失效反馈

官方服务：

资源简介：

Mycobacterium tuberculosis antigen 85 is induced in vitro by isoniazid (INH); its sustained induction in sputum during tuberculosis (TB) therapy predicts relapse. In this trial, rifampin or rifalazil inhibited the induction of sputum antigen 85 by INH in a dose-dependent fashion. This approach may facilitate the evaluation of new TB drugs.

提供机构：

American Society for Microbiology (ASM)