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Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity. Xu et al

NIAID Data Ecosystem2026-05-02 收录

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JAK-STAT信号通路

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https://data.mendeley.com/datasets/g4sb5pdtyy 数据链接链接失效反馈

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Original data from the images and western blots from the paper: Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity.

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创建时间：

2024-06-24

自身免疫疾病机制

细胞表型鉴定

Pathogenic T helper cells (Th cells) that respond to self-antigen cannot be easily distinguished from beneficial Th cells. These cells can generate systemic autoimmune disease in response to widely-ex

NIAID Data Ecosystem90

Genetically-driven target tissue over-expression of CD40: A novel mechanism in autoimmune disease

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免疫病理学

The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid derived cells, many of which are targets for tissue specific autoimmune diseases, including d thyroi

NIAID Data Ecosystem50

"Increase Cytokine Levels in Seronegative Myositis: Potential IL-23 driven Th17 Immune Response Implications" raw data

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Th17细胞因子通路

Raw data from manuscript " Increase Cytokine Levels in Seronegative Myositis: Potential Th17 Immune Response Implications "

DataCite Commons2024-09-11 更新40

H3K27me3 ChIP-seq of naïve CD4 T cells. H3K27me3 ChIP-seq of naïve CD4 T cells

细胞表观遗传学

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Differentiation and activation of T cells require the activity of numerous histone lysine methyltransferases (HMT) that control the transcriptional T cell output. One of the most potent regulators of

NIAID Data Ecosystem60

Supporting data for "The role of AIM2 inflammasome in Systemic Lupus Erythematosus"

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炎症小体功能

Systemic Lupus Erythematosus is a chronic autoimmune condition in which the body mistakenly attacks itself. It’s aetiopathogenesis is highly complex. Increasing evidence suggests that the innate immun

DataCite Commons2021-09-15 更新50

Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity. Xu et al

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