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UBC9 knockdown in bladder cancer T24 cell lines

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117143
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UBC9 is the sole conjugating enzyme E2 in the sumoylation and plays a pivotal role in maintaining homeostasis and restraining stress reaction. Targeting UBC9 is emerging as a novel strategy for cancer therapy. However, the role of UBC9 in bladder cancer is not clear. Here, we sought to determine the alterations of trancriptome after shRNA-mediated knockdown UBC9 in T24 cell lines. Knockdown of UBC9 was performed in T24 cell lines with controls, respcectively. A total of 6 samples (3 knockdown with 3 controls) were used for RNA sequencing analysis.
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2020-12-01
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