wanessa GOES - Table_S3.xlsx

Using normalized read depth analysis to assess gene copy number variation in the PH8 strain, we identified 205 genes presenting a somy greater than 1.8. Among these genes that were considered supernumerary or expanded, 104 encode hypothetical proteins, with unknown function. Multigene families encoding amino acid transporters, serine threonine phosphatase, ferredoxins, kinases, calpains, and GP63 metalloproteases are among the supernumerary genes with known function, several of them, being characterized as virulence factors and are discussed in the next section. Gene ontology analysis on the expanded genes showed that this group is enriched for genes involved in biological process related to transmembrane transport (8 genes) and lipid metabolism (13 genes), representing 447 haploid copies in PH8 genome.