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The ubiquitin ligase HUWE1 regulates hematopoietic stem cell maintenance and lymphoid commitment [microarray]

ChEBI2016-08-20 更新2026-07-12 收录

造血干细胞调控

E3泛素连接酶功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-85832 数据链接链接失效反馈

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资源简介：

The ubiquitin ligase HUWE1 regulates hematopoietic stem cell maintenance and lymphoid commitment [microarray]

应用场景：

创建时间：

2016-08-20

生殖生物学

E3泛素连接酶功能

Additional file 18. Raw data. This file contains raw data with individual data of replicates for Figs. 2A, 3A-B, 4C, 4E, S5, S6, S7, S8, S9, and S10 (i.e., those experiments in which n < 6).

Figshare2022-07-14 更新80

Musashi 2 is a regulator of the hematopoietic stem cell compartment identified by a retroviral insertion screen and knockout mice

造血干细胞调控

基因功能研究

Musashi 2 is a regulator of the hematopoietic stem cell compartment identified by a retroviral insertion screen and knockout mice

ChEBI2011-05-21 更新20

Inhibition of DEK contributes to the tolerance of replication stress and restores HSC function in Fanconi anemia (8-ATAC). Inhibition of DEK contributes to the tolerance of replication stress and restores HSC function in Fanconi anemia (8-ATAC)

范可尼贫血分子机制

造血干细胞调控

Replication stress drives functional decline in HSCs and is a major driver of BM failure in Fanconi anemia (FA). At present, how HSCs respond and counteract replication stress remains largely unknown.

NIAID Data Ecosystem10

Genome-Wide Survey and Expression Analysis of Chlamydomonas reinhardtii U-box E3 Ubiquitin Ligases (CrPUBs) Reveal a Functional Lipid Metabolism Module

微藻代谢

E3泛素连接酶功能

E3 ubiquitin ligases determine the substrate specificity of ubiquitination. Plant U-box (PUB) E3 ligases, with a typical 70-amino acid U-box domain, participate in plant developmental processes and en

Figshare2016-01-15 更新50

A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia

白血病

造血干细胞调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20