Crystal Structures of Human Prostatic Acid Phosphatase in Complex with a Phosphate Ion and alpha-Benzylaminobenzylphosphonic Acid Update the Mechanistic Picture and Offer New Insights into Inhibitor Design

Crystal Structures of Human Prostatic Acid Phosphatase in Complex with a Phosphate Ion and alpha-Benzylaminobenzylphosphonic Acid Update the Mechanistic Picture and Offer New Insights into Inhibitor Design Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ortlund, E, LaCount, M.W, Lebioda, L. Deposit date: 2002-12-07 Release date: 2002-12-20 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design Biochemistry, 42, 2003人前列腺酸性磷酸酶与磷酸根离子及α-苄基氨基苄基膦酸复合物的晶体结构：更新对作用机制的认知并为抑制剂设计提供全新视角 描述符：2-乙酰氨基-2-脱氧-α-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖…… 作者：Ortlund, E、LaCount, M.W、Lebioda, L. 沉积日期：2002-12-07 发布日期：2002-12-20 末次修改日期：2024-12-25 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.9 Å 引用：人前列腺酸性磷酸酶与磷酸根离子及α-苄基氨基苄基膦酸复合物的晶体结构更新对作用机制的认知并为抑制剂设计提供全新视角 // 《生物化学（Biochemistry）》，42卷，2003年