Human Clariom D Transcriptome profiling of microRNA-mediated neuronal reprogramming with PTBP2 knockdown

To identify PTBP2 targets important for neural fate acqusition, miR-9/9*-124-mediated direct conversion of human fibroblasts into neurons was employed. We showed that PTBP2 is important for the successful acquisition of neuronal fate and profiled fibroblasts and reprogrammed neurons with and without PTBP2 knockdown to identify neuronal-associated PTBP2 targets during reprogramming. Human Clariom D array profiling of 3 sets of samples each with duplicates at day 14 with miR-NS, miR-9/9*-124 shCTL and miR-9/9*-124 shPTBP2