five

RasV12 blocks DNA synthesis and DNA damage response

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE127228
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Transcriptional profile of RasV12 expressing cells shows an upregulation of RTK signalling genes and a downregulation in genes involved in DNA sintesis and DNA damage response. mRNA expression profiles of GFP-i and RasV12 expressing drosophila wing imaginal cells. Transgenes where expressed for 3 days at 29ºC under the control of the Ap>Gal4 driver. Cells where labelled by the expression of myristolated Tomate and FACS sorted based on this expression.
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2019-07-02
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