Identification of voltage-gated sodium channel NaV1.7 inhibitors for chronic pain therapeutic development is an area of vigorous pursuit. In an effort to identify more potent leads compared to our pre

NIAID Data Ecosystem60

Rat Pain Paper 3-25-2024

疼痛机制研究

动物模型实验

File 1: Body Composition DataFile 2: Cytokine Array dataFile 3: Statistical analyses including means/sems/N values

Figshare2024-03-25 更新50

Additional file 5 of Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain

疼痛机制研究

表观遗传调控

Additional file 5: Supplemental Table 4. Transcriptional factor motifs significantly enriched in differentially accessible regions after CCI.

NIAID Data Ecosystem70

Transcriptomic profiling of DRG in a sickle mouse model. Mus musculus

疼痛机制研究

镰状细胞病基因型

In order to identify global targets associated with chronic pain and changes associated with transition from acute to chronic pain in SCD, we performed RNA sequencing analysis from the dorsal root gan

NIAID Data Ecosystem50

Mechanism of dual NaV1.7 and NaV1.8 block by a NaV inhibitory peptide aptamer

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