Sertraline is one of the most prescribed antidepressants, but its pharmacokinetic (PK) properties are still not completely characterized. Using non-linear mixed-effects modeling (NONMEM) we examined f
Demographic data Study Description This was a phase I, open-label, pharmacokinetic (PK) study with a primary objective of determining PK of sildenafil in premature infants. The trial enrolled 25 prema
Background: Several studies have investigated the population pharmacokinetics (popPK) of valproic acid (VPA) in children with epilepsy. However, the predictive performance of these models in the extra
