Genome sequencing of wildtype hMSCs and ones with constitutive activation of endogenous NRF2. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA336119
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资源简介:
We generated hMSCs with constitutive activation of endogenous NRF2 via targeted gene editing. CNV analyses were compared between NRF2 wildtype and AG/AG hMSCs with or without multi-hits system for human cell oncogenic transformation. The result showed that sustained NRF2 activity help safeguard genome stability of hMSCs against oncogenic insults.
创建时间:
2016-08-02



