Incremental effect of allelotypes in BCL11A and HBE on Baseline and Maximum HbF%.
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Baseline HbF%: Trend analysis across allelotypes: F(df,3) = 8.48, ptrend = 0.004.Maximum HbF%: Trend analysis across 0 or ≥1 A alleles: F(df,2) = 7.43, ptrend = 0.009.The + denotes minor allele (A) associated with higher HbF%; the - denotes the other allele (G),with the BCL11A A or HBE allele in 1 or 2 copies.*Reference allelotype.**Not significant when adjusted for baseline HbF.#Includes subjects with either or both minor A alleles.
创建时间：
2015-12-02
