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OXPHOS driven by glycolysis through the malate aspartate shuttle is required for cardiomyocyte re-differentiation and long-term fish heart regeneration

NIAID Data Ecosystem2026-05-02 收录

心脏再生

心肌细胞代谢机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE234990 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-08-01

心脏再生

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While Astyanax mexicanus surface fish regenerate their heart after injury, their PachÃ³n cave-dwelling counterparts cannot and form a permanent fibrotic scar. To identify differences in gene expressio

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Transcriptome-wide profiling of thyroid hormone and adrenergic interactions in the mouse heart. Transcriptome-wide profiling of thyroid hormone and adrenergic interactions in the mouse heart

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心肌细胞增殖

During the first weeks after birth, cardiomyocytes within the mouse heart progressively exit the cell cycle, binucleate, and lose regenerative capacity. We have determined that combined pharmacologica

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Telomerase is essential for zebrafish heart regeneration

心脏再生

端粒酶

Unlike human hearts, zebrafish hearts efficiently regenerate after injury. Regeneration is driven by the strong proliferation response of its cardiomyocytes to injury. In this study, we show that acti

干细胞与再生医学数据中心2022-02-20 更新70

H3K27me3 deposition over sarcomeric and cytoskeletal promoters is required for cardiomyocyte cytokinesis and wound invasion during zebrafish heart regeneration [ChIP-seq]

心脏再生

表观遗传学

Deciphering the genetic and epigenetic regulation of injury-induced heart regeneration in organisms capable of robust cardiac renewal represents an attractive inroad towards regenerating the human hea

干细胞与再生医学数据中心2022-02-20 更新60

OXPHOS driven by glycolysis through the malate aspartate shuttle is required for cardiomyocyte re-differentiation and long-term fish heart regeneration

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