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Nuclear receptor activation leads to functional changes in CTCF-defined chromatin structure [Hi-C]

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NIAID Data Ecosystem2026-03-13 收录
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The aim of the project was to investigate the effect of nuclear receptor activation, particularly of the vitamin D receptor, on chromatin structure, and associated functional changes in the transcriptional response of THP-1 cells. HiC was performed on THP-1 cells, with either control (24 h vehicle) or 24 h 100 nM 1,25(OH)2D3 treatment.

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2022-04-29
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